Originally Derbe was part of the ancient kingdom of Lycaonia, but when Rome redivided Asia Minor, Derbe became part of the Roman province of Galatia (Acts 14:6; see GALATIA; LYCAONIA). Paul and Barnabas established a church in Derbe on their first missionary journey (Acts 14:20-21), and Paul visited the church on his second and third journeys (Acts 16:1; 18:23). It was one of the churches that Paul wrote to in his letter to the Galatians.

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